Explained: How Does the Bundibugyo Strain of Ebola in the Current Outbreak Differ From the Type that Ravaged Liberia Between 2014 -2016

Published: May 25, 2026

Last updated: August 29, 2026

The recent Ebola outbreak reported in parts of Uganda and the Democratic Republic of Congo (DRC) has renewed public concern across Africa, including Liberia, a country once ravaged by the virus.

However, health experts say the outbreak involves a different strain of the Ebola virus known as the Bundibugyo strain, which differs from the strain responsible for the deadly West African Ebola outbreak that affected Liberia between 2014 and 2016.

According to the World Health Organization (WHO), Ebola Virus Disease (EVD) is a severe and often fatal illness caused by viruses within the Ebolavirus family. Scientists have identified several Ebola species, including the Zaire, Sudan, and Bundibugyo strains.

The Ebola outbreak that devastated Liberia was caused primarily by the Zaire ebolavirus, one of the deadliest Ebola strains known to science. The U.S. Centers for Disease Control and Prevention (CDC) explains that the Zaire strain has historically recorded very high fatality rates during outbreaks, sometimes reaching up to 90 percent in poorly controlled epidemics.

In contrast, the Bundibugyo ebolavirus (BDBV) was first identified in Uganda’s Bundibugyo District in 2007. According to the National Institutes of Health (NIH), the Bundibugyo strain is generally considered less deadly than the Zaire strain, with estimated fatality rates ranging between 25 and 50 percent during previous outbreaks.

Medical experts say one of the most important differences between the two strains is the availability of vaccines and treatments. During the West African Ebola outbreak, scientists developed vaccines such as Ervebo, which specifically target the Zaire strain. The U.S. Food and Drug Administration (FDA) approved the vaccine for preventing Ebola caused by Zaire ebolavirus.

However, researchers continue to study vaccines and therapies for the Bundibugyo strain because existing Ebola vaccines may not provide the same level of protection against all Ebola species. The WHO notes that outbreak response strategies may vary depending on the specific Ebola strain involved.

Another key difference involves testing and diagnosis. According to the Johns Hopkins Bloomberg School of Public Health, laboratory tests designed for one Ebola strain may require modification or additional confirmation when detecting other strains like Bundibugyo. This can sometimes slow early outbreak detection and response efforts.

Despite these differences, both Ebola strains spread in similar ways. The CDC explains that Ebola spreads through direct contact with bodily fluids such as blood, vomit, saliva, sweat, urine, or contaminated materials from infected individuals. Symptoms often include fever, weakness, vomiting, diarrhea, bleeding, and organ complications.

Public health experts continue to emphasize that Liberia has not reported any confirmed Ebola case linked to the current outbreak. Nevertheless, Liberian health authorities remain vigilant because of the country’s painful experience during the 2014–2016 epidemic.

Medical experts say understanding the differences between Ebola strains is important because treatment approaches, vaccines, surveillance systems, and outbreak responses may differ depending on the specific virus involved. They also stress that public awareness and early reporting remain critical in preventing future outbreaks from spreading across borders.

To conclude, the Bundibugyo strain of Ebola is a rare type of Ebola virus first discovered in Uganda in 2007 and is different from the Zaire strain that caused the deadly 2014–2016 Ebola outbreak in Liberia. According to medical sources, including the World Health Organization (WHO), the U.S. Centers for Disease Control and Prevention (CDC), and the National Institutes of Health (NIH), the Bundibugyo strain is generally considered less deadly than the Zaire strain and currently has fewer approved vaccines and treatments specifically designed for it.

While both strains spread through direct contact with infected bodily fluids and cause similar symptoms such as fever, vomiting, diarrhea, and bleeding, experts say understanding the differences between Ebola strains is important because testing methods, vaccines, and outbreak response strategies may vary depending on the specific virus involved.